AMICUS THERAPEUTICS, INC.
FOLDHealthcare · Pharmaceutical Preparations · DE · SEC filings ↗ · Compare ⊕
View price & chart on Yahoo Finance ↗Financials
SEC XBRL · annual| FY25 | FY24 | FY23 | FY22 | FY21 | FY20 | |
|---|---|---|---|---|---|---|
| Revenue | $634.2M | $528.3M | $399.4M | $329.2M | $305.5M | $260.9M |
| Operating income | $32.8M | $24.9M | −$77.2M | −$212.1M | −$206.4M | −$247.0M |
| Net income | −$27.1M | −$56.1M | −$151.6M | −$236.6M | −$250.5M | −$276.9M |
| Total assets | $949.9M | $785.0M | $777.9M | $724.2M | $905.1M | $886.5M |
| Total liabilities | $675.6M | $591.0M | $617.7M | $601.1M | $597.8M | $600.1M |
| Equity | $274.2M | $194.0M | $160.2M | $123.0M | $307.4M | $286.4M |
| EPS (diluted) | $-0.09 | $-0.18 | $-0.51 | $-0.82 | $-0.92 | $-1.07 |
| Shares out. | 300.1M | 295.4M | 282.7M | 280.0M | 264.3M | 257.2M |
Reported figures from the company's SEC filings (XBRL). Blank where a line item isn't cleanly tagged — never estimated.
Key ratios
from filings · FY2025- Operating margin
- 5.2%
- Net margin
- −4.3%
- Return on equity
- −9.9%
- Return on assets
- −2.9%
- Return on capital (ROCE)
- 4.6%
- Liabilities / assets
- 71.1%
- Debt / equity
- 2.46×
- Book value / share
- $0.91
- Revenue growth (YoY)
- 20.0%
- Net income growth (YoY)
- —
Computed from the company's own SEC figures — no market price, so these are facts, not a valuation. Book value per share is reported equity ÷ shares; it is not the stock price.
Financial health
forensic scores · FY2025- Altman Z″ (distress)
- -5.81distress
- Accruals / assets
- −6.3%clean
- Beneish M-Score
- -2.69normal
- Piotroski F-Score
- 5/9mixed
Altman Z″is a textbook bankruptcy-distress score from book values only (>2.6 safe · 1.1–2.6 grey · <1.1 distress). Accruals = (net income − operating cash flow) ÷ assets; persistently high accruals are an earnings-quality red flag. Beneish M-Scoreis an eight-ratio screen comparing this year with last (M > −1.78 = elevated manipulation-risk screen, not proof). Piotroski F-Scorecounts how many of nine fundamental-health checks pass (shown as passed / applicable; we use operating margin and total liabilities as documented proxies where the exact input isn't XBRL-tagged). Computed from SEC filings — descriptive factors, not advice or a forecast.
Quality score
EDS ScoreOur own multi-factor score from free SEC data — profitability, growth, financial strength, earnings quality, and event/ownership catalysts. No market price and no licensed model: each axis is the share of source-backed checks it passes. Descriptive factors, not advice or a forecast.
Signs
● 1 severe● 2 warning● 4 good- Altman Z″ in the distress zone
- Reported a net loss
- High leverage (liabilities > 70% of assets)
- Operating margin is positive
- Revenue is growing year-over-year
- Positive operating cash flow
- Clean earnings (low accruals)
Derived from the company's own SEC figures (fundamentals, forensic scores, filing discipline) — descriptive factors, not advice or a forecast.
Clinical trials
ClinicalTrials.gov · ongoing · next readout first- Phase 3Active Not Recruitingreadout ~2026-06ZIP Study-OL Study of Safety, PK, Efficacy, PD, Immunogenicity of ATB200/AT2221 in Pediatrics Aged 0 to < 18 y.o. w/LOPD
- Phase 3Active Not Recruitingreadout ~2026-12-31A Study to Evaluate Migalastat in Fabry Subjects With Amenable GLA Variant and Renal Disease
- Phase 3Recruitingreadout ~2027-07A Study to Evaluate the Safety, Efficacy, PK, PD and Immunogenicity of Cipaglucosidase Alfa/Miglustat in IOPD Subjects Aged 0 to <18
- Phase 3Recruitingreadout ~2027-12A Study of Migalastat in Pediatric Subjects (2 to <12 Yrs) With Fabry Disease and Amenable GLA Variants
Interventional studies led by this company. “Readout” is the trial's primary-completion date — an estimate the sponsor reports, not a guarantee.
5%+ owners
SEC Schedule 13D / 13G · last 3 yrs- Barclays PlcPassive (13G)May 14, 2026
- Goldman Sachs Group IncPassive (13G)May 11, 2026
- Ubs Group AgPassive (13G)May 7, 2026
- Glazer Capital, LlcPassive (13G)May 1, 2026
- Vanguard Capital Management LlcPassive (13G)Apr 29, 2026
- Vanguard Group IncPassive (13G)Mar 26, 2026
- Wellington Management Group LlpPassive (13G)Feb 10, 2026
- William Blair Investment Management, LlcPassive (13G)Feb 9, 2026
- Avoro Capital Advisors LlcPassive (13G)Nov 14, 2025
- Perceptive Advisors LlcPassive (13G)Aug 14, 2025
- Blackrock, Inc.Passive (13G)Apr 23, 2025
- Redmile Group, LlcPassive (13G)Feb 14, 2025
Holders who disclosed a 5%+ stake. 13D signals intent to influence or control; 13G is a passive holding. Latest filing per holder — open it for the exact stake.
Short interest
FINRA · bi-monthly| Settlement | Shares short | Days to cover | Δ vs prior |
|---|---|---|---|
| Apr 15, 2026 | 21.9M | 7.5 | +3.9% |
| Mar 31, 2026 | 21.1M | 5.7 | +4.5% |
| Mar 13, 2026 | 20.2M | 5.5 | +6.3% |
| Feb 27, 2026 | 19.0M | 6.2 | +7.6% |
| Feb 13, 2026 | 17.6M | 2.2 | -1.8% |
Shares sold short as reported to FINRA. Days-to-cover = short shares ÷ average daily volume — higher means more potential squeeze pressure.
Material events
SEC Form 8-K · most recent- Terminated a material agreement · Completed an acquisition or disposition · Delisting / listing-standard notice · Modified shareholder rights · Change in control · Director / officer change · Amended charter or bylawsApr 27, 2026
- Other material eventApr 23, 2026
- Shareholder voteMar 3, 2026
- Results of operationsFeb 20, 2026
- Results of operations · Regulation FD disclosureJan 26, 2026
- Entered a material agreement · Amended charter or bylaws · Regulation FD disclosureDec 19, 2025
- Results of operationsNov 4, 2025
- Results of operationsJul 31, 2025
Events the company reported on Form 8-K, labelled by the SEC item code it filed under — its own classification, not our interpretation.
Recent SEC filings
All filings ↗- SCHEDULE 13GMay 14, 2026
- SCHEDULE 13GMay 11, 2026
- SCHEDULE 13GMay 7, 2026
- 15-12GMay 7, 2026
- SCHEDULE 13GMay 1, 2026
- EFFECTApr 29, 2026
- EFFECTApr 29, 2026
- EFFECTApr 29, 2026
- EFFECTApr 29, 2026
- EFFECTApr 29, 2026
- EFFECTApr 29, 2026
- EFFECTApr 29, 2026
- EFFECTApr 29, 2026
- SCHEDULE 13GApr 29, 2026
- 4Apr 27, 2026