CytomX Therapeutics, Inc.
CTMXNasdaqHealthcare · Pharmaceutical Preparations · DE · SEC filings ↗ · Compare ⊕
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SEC XBRL · annual| FY25 | FY24 | FY23 | FY22 | FY21 | FY20 | |
|---|---|---|---|---|---|---|
| Revenue | $76.2M | $138.1M | $101.2M | $53.2M | $37.3M | $100.4M |
| Operating income | −$22.4M | $25.0M | −$6.5M | −$101.3M | −$116.0M | −$48.6M |
| Net income | −$17.4M | $31.9M | −$569,000 | −$99.3M | −$115.9M | −$32.9M |
| Total assets | $151.6M | $120.5M | $201.8M | $260.9M | $339.4M | $358.7M |
| Total liabilities | $52.6M | $121.0M | $249.2M | $346.6M | $339.9M | $308.9M |
| Equity | $99.0M | −$456,000 | −$47.4M | −$85.8M | −$459,000 | $49.8M |
| EPS (diluted) | — | — | — | — | — | — |
| Shares out. | 170.2M | 67.7M | 66.2M | 65.4M | 64.8M | 45.6M |
Reported figures from the company's SEC filings (XBRL). Blank where a line item isn't cleanly tagged — never estimated.
Key ratios
from filings · FY2025- Operating margin
- −29.3%
- Net margin
- −22.8%
- Return on equity
- −17.5%
- Return on assets
- −11.5%
- Return on capital (ROCE)
- −21.3%
- Liabilities / assets
- 34.7%
- Debt / equity
- 0.53×
- Book value / share
- $0.58
- Revenue growth (YoY)
- −44.8%
- Net income growth (YoY)
- −154.5%
Computed from the company's own SEC figures — no market price, so these are facts, not a valuation. Book value per share is reported equity ÷ shares; it is not the stock price.
Financial health
forensic scores · FY2025- Altman Z″ (distress)
- -10.12distress
- Accruals / assets
- 38.4%high accruals
- Piotroski F-Score
- 2/9weak
Altman Z″is a textbook bankruptcy-distress score from book values only (>2.6 safe · 1.1–2.6 grey · <1.1 distress). Accruals = (net income − operating cash flow) ÷ assets; persistently high accruals are an earnings-quality red flag. Beneish M-Scoreis an eight-ratio screen comparing this year with last (M > −1.78 = elevated manipulation-risk screen, not proof). Piotroski F-Scorecounts how many of nine fundamental-health checks pass (shown as passed / applicable; we use operating margin and total liabilities as documented proxies where the exact input isn't XBRL-tagged). Computed from SEC filings — descriptive factors, not advice or a forecast.
Quality score
EDS ScoreOur own multi-factor score from free SEC data — profitability, growth, financial strength, earnings quality, and event/ownership catalysts. No market price and no licensed model: each axis is the share of source-backed checks it passes. Descriptive factors, not advice or a forecast.
Signs
● 1 severe● 5 warning● 1 good- Altman Z″ in the distress zone
- Operating losses (negative operating margin)
- Reported a net loss
- Revenue declined year-over-year
- Negative operating cash flow
- High accruals — earnings-quality risk
- Conservative leverage (liabilities < 50% of assets)
Derived from the company's own SEC figures (fundamentals, forensic scores, filing discipline) — descriptive factors, not advice or a forecast.
Clinical trials
ClinicalTrials.gov · ongoing · next readout first- Phase 1Recruitingreadout ~2027-11-30First In Human Study of CX-2051 in Advanced Solid Tumors
- Phase 1Recruitingreadout ~2028-02-28First In Human Study of CX-801 in Advanced Solid Tumors
Interventional studies led by this company. “Readout” is the trial's primary-completion date — an estimate the sponsor reports, not a guarantee.
5%+ owners
SEC Schedule 13D / 13G · last 3 yrs- Kynam Capital Management, LpPassive (13G)May 15, 2026
- Venrock Healthcare Capital Partners Iii, L.P.Passive (13G)May 15, 2026
- Longitude Capital Partners V, LlcPassive (13G)May 15, 2026
- Perceptive Advisors LlcPassive (13G)May 15, 2026
- Seven Fleet Capital Management LpPassive (13G)May 15, 2026
- Point72 Asset Management, L.P.Passive (13G)Apr 16, 2026
- Vanguard Group IncPassive (13G)Mar 26, 2026
- Tang Capital Management LlcPassive (13G)Feb 17, 2026
- Orbimed Advisors LlcPassive (13G)Feb 17, 2026
- Fmr LlcPassive (13G)Feb 5, 2026
- Biotechnology Value Fund L PPassive (13G)Jul 9, 2025
- Seven Fleet Partners LpPassive (13G)May 20, 2025
Holders who disclosed a 5%+ stake. 13D signals intent to influence or control; 13G is a passive holding. Latest filing per holder — open it for the exact stake.
Short interest
FINRA · bi-monthly| Settlement | Shares short | Days to cover | Δ vs prior |
|---|---|---|---|
| May 15, 2026 | 31.1M | 10.3 | +4.7% |
| Apr 30, 2026 | 29.7M | 8.4 | +8.1% |
| Apr 15, 2026 | 27.5M | 5.4 | +24.9% |
| Mar 31, 2026 | 22.0M | 1.1 | +7.9% |
| Mar 13, 2026 | 20.4M | 7.1 | +8.2% |
Shares sold short as reported to FINRA. Days-to-cover = short shares ÷ average daily volume — higher means more potential squeeze pressure.
Material events
SEC Form 8-K · most recent- Results of operationsMay 7, 2026
- Other material eventMar 19, 2026
- Results of operationsMar 16, 2026
- Results of operationsNov 6, 2025
- Other material eventAug 13, 2025
- Results of operationsAug 7, 2025
- Director / officer change · Shareholder voteJun 13, 2025
- Other material eventMay 28, 2025
Events the company reported on Form 8-K, labelled by the SEC item code it filed under — its own classification, not our interpretation.
Recent SEC filings
All filings ↗- SCHEDULE 13G/AMay 15, 2026
- SCHEDULE 13G/AMay 15, 2026
- SCHEDULE 13G/AMay 15, 2026
- SCHEDULE 13G/AMay 15, 2026
- SCHEDULE 13G/AMay 15, 2026
- 8-KMay 7, 2026
- 10-QMay 7, 2026
- DEFA14AApr 30, 2026
- DEF 14AApr 30, 2026
- PRE 14AApr 20, 2026
- SCHEDULE 13GApr 16, 2026
- SCHEDULE 13G/AMar 26, 2026
- 4Mar 19, 2026
- 4Mar 19, 2026
- 4Mar 19, 2026
Event-driven situations (1)
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