Blueprint Medicines Corp
BPMCHealthcare · Pharmaceutical Preparations · DE · SEC filings ↗ · Compare ⊕
View price & chart on Yahoo Finance ↗Financials
SEC XBRL · annual| FY24 | FY23 | FY22 | FY21 | FY20 | FY19 | |
|---|---|---|---|---|---|---|
| Revenue | $508.8M | $249.4M | $204.0M | $180.1M | $793.7M | $66.5M |
| Operating income | — | — | — | — | — | — |
| Net income | −$67.1M | −$507.0M | −$557.5M | −$644.1M | $313.9M | −$347.7M |
| Total assets | $1.18B | $1.05B | $1.35B | $1.25B | $1.72B | $707.7M |
| Total liabilities | $881.1M | $918.6M | $835.2M | $281.5M | $248.3M | $243.3M |
| Equity | $298.7M | $130.6M | $514.7M | $970.7M | $1.47B | $464.4M |
| EPS (diluted) | $-1.07 | $-8.37 | $-9.35 | $-11.01 | $5.59 | $-7.27 |
| Shares out. | 61.2M | 60.0M | 59,203 | 58.0M | 54.0M | 44.1M |
Reported figures from the company's SEC filings (XBRL). Blank where a line item isn't cleanly tagged — never estimated.
Key ratios
from filings · FY2024- Operating margin
- —
- Net margin
- −13.2%
- Return on equity
- −22.5%
- Return on assets
- −5.7%
- Return on capital (ROCE)
- —
- Liabilities / assets
- 74.7%
- Debt / equity
- 2.95×
- Book value / share
- $4.88
- Revenue growth (YoY)
- 104.0%
- Net income growth (YoY)
- —
Computed from the company's own SEC figures — no market price, so these are facts, not a valuation. Book value per share is reported equity ÷ shares; it is not the stock price.
Financial health
forensic scores · FY2024- Accruals / assets
- 10.6%high accruals
- Beneish M-Score
- -0.77elevated
- Piotroski F-Score
- 3/8weak
Altman Z″is a textbook bankruptcy-distress score from book values only (>2.6 safe · 1.1–2.6 grey · <1.1 distress). Accruals = (net income − operating cash flow) ÷ assets; persistently high accruals are an earnings-quality red flag. Beneish M-Scoreis an eight-ratio screen comparing this year with last (M > −1.78 = elevated manipulation-risk screen, not proof). Piotroski F-Scorecounts how many of nine fundamental-health checks pass (shown as passed / applicable; we use operating margin and total liabilities as documented proxies where the exact input isn't XBRL-tagged). Computed from SEC filings — descriptive factors, not advice or a forecast.
Quality score
EDS ScoreOur own multi-factor score from free SEC data — profitability, growth, financial strength, earnings quality, and event/ownership catalysts. No market price and no licensed model: each axis is the share of source-backed checks it passes. Descriptive factors, not advice or a forecast.
Signs
● 5 warning● 1 good- Reported a net loss
- High leverage (liabilities > 70% of assets)
- Negative operating cash flow
- High accruals — earnings-quality risk
- Beneish M-Score elevated — earnings-manipulation screen flag
- Revenue is growing year-over-year
Derived from the company's own SEC figures (fundamentals, forensic scores, filing discipline) — descriptive factors, not advice or a forecast.
FDA-approved drugs
openFDA · most recent- GAVRETODec 1, 2020
- AYVAKITJan 9, 2020
Clinical trials
ClinicalTrials.gov · ongoing · next readout first- Phase 2Recruitingreadout ~2026-12-31Study of BLU-808 in Chronic Inducible Urticaria (CIndU) and Chronic Spontaneous Urticaria (CSU)
- Phase 2Active Not Recruitingreadout ~2027-06-23(PIONEER) Study to Evaluate Efficacy and Safety of Avapritinib (BLU-285), A Selective KIT Mutation-targeted Tyrosine Kinase Inhibitor, Versus Placebo in Patients With Indolent Systemic Mastocytosis
- Phase 4Recruitingreadout ~2027-12-31Avapritinib Rollover Study
- Phase 2/3Recruitingreadout ~2032-09-30(HARBOR) Study to Evaluate Efficacy and Safety of BLU-263 Versus Placebo in Patients With Indolent Systemic Mastocytosis
Interventional studies led by this company. “Readout” is the trial's primary-completion date — an estimate the sponsor reports, not a guarantee.
5%+ owners
SEC Schedule 13D / 13G · last 3 yrs- Pentwater Capital Management LpPassive (13G)Aug 14, 2025
- Avoro Capital Advisors LlcPassive (13G)Aug 14, 2025
- Price T Rowe Associates Inc /Md/Passive (13G)Aug 14, 2025
- Davidson Kempner Capital Management LpPassive (13G)Jul 21, 2025
- Wellington Management Group LlpPassive (13G)May 12, 2025
- Blackrock, Inc.Passive (13G)Apr 23, 2025
- Fmr LlcPassive (13G)Feb 12, 2025
Holders who disclosed a 5%+ stake. 13D signals intent to influence or control; 13G is a passive holding. Latest filing per holder — open it for the exact stake.
Short interest
FINRA · bi-monthly| Settlement | Shares short | Days to cover | Δ vs prior |
|---|---|---|---|
| Jul 15, 2025 | 1.7M | 1.0 | -54.7% |
| Jun 30, 2025 | 3.7M | 1.1 | +17.6% |
| Jun 13, 2025 | 3.1M | 1.0 | -48.6% |
| May 30, 2025 | 6.1M | 8.7 | +7.4% |
| May 15, 2025 | 5.7M | 6.0 | +0.2% |
Shares sold short as reported to FINRA. Days-to-cover = short shares ÷ average daily volume — higher means more potential squeeze pressure.
Material events
SEC Form 8-K · most recent- Terminated a material agreement · Completed an acquisition or disposition · Delisting / listing-standard notice · Modified shareholder rights · Change in control · Director / officer change · Amended charter or bylaws · Other material eventJul 18, 2025
- Shareholder voteJun 20, 2025
- Entered a material agreement · Other material eventJun 2, 2025
- Results of operationsMay 1, 2025
- Results of operationsFeb 13, 2025
- Regulation FD disclosureJan 13, 2025
- Other material eventDec 18, 2024
- Results of operationsOct 30, 2024
Events the company reported on Form 8-K, labelled by the SEC item code it filed under — its own classification, not our interpretation.
Recent SEC filings
All filings ↗- SCHEDULE 13GAug 14, 2025
- SCHEDULE 13G/AAug 14, 2025
- SCHEDULE 13G/AAug 14, 2025
- 15-12GJul 29, 2025
- EFFECTJul 24, 2025
- 4OWNERSHIP DOCUMENTJul 21, 2025
- 4OWNERSHIP DOCUMENTJul 21, 2025
- 4OWNERSHIP DOCUMENTJul 21, 2025
- 4OWNERSHIP DOCUMENTJul 21, 2025
- 4OWNERSHIP DOCUMENTJul 21, 2025
- 4OWNERSHIP DOCUMENTJul 21, 2025
- 4OWNERSHIP DOCUMENTJul 21, 2025
- 4OWNERSHIP DOCUMENTJul 21, 2025
- 4OWNERSHIP DOCUMENTJul 21, 2025
- 4OWNERSHIP DOCUMENTJul 21, 2025