Stoke Therapeutics, Inc.
STOKNasdaqHealthcare · Pharmaceutical Preparations · DE · SEC filings ↗ · Compare ⊕
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SEC XBRL · annual| FY25 | FY24 | FY23 | FY22 | FY21 | FY20 | |
|---|---|---|---|---|---|---|
| Revenue | $184.4M | $36.6M | $8.8M | $12.4M | — | — |
| Operating income | −$20.6M | −$101.4M | −$114.8M | −$104.4M | −$86.1M | −$53.0M |
| Net income | −$6.9M | −$89.0M | −$104.7M | −$101.1M | −$85.8M | −$52.2M |
| Total assets | $418.4M | $271.6M | $228.3M | $256.1M | $238.9M | $297.9M |
| Total liabilities | $66.0M | $42.5M | $68.8M | $71.2M | $21.1M | $11.8M |
| Equity | $352.5M | $229.0M | $159.6M | $184.8M | $217.8M | $286.1M |
| EPS (diluted) | $-0.12 | $-1.65 | $-2.38 | $-2.60 | $-2.34 | — |
| Shares out. | 54.1M | 46.3M | 44.1M | 37.4M | 36.7M | 32.9M |
Reported figures from the company's SEC filings (XBRL). Blank where a line item isn't cleanly tagged — never estimated.
Key ratios
from filings · FY2025- Operating margin
- −11.2%
- Net margin
- −3.7%
- Return on equity
- −2.0%
- Return on assets
- −1.6%
- Return on capital (ROCE)
- −5.7%
- Liabilities / assets
- 15.8%
- Debt / equity
- 0.19×
- Book value / share
- $6.52
- Revenue growth (YoY)
- 404.5%
- Net income growth (YoY)
- —
Computed from the company's own SEC figures — no market price, so these are facts, not a valuation. Book value per share is reported equity ÷ shares; it is not the stock price.
Financial health
forensic scores · FY2025- Altman Z″ (distress)
- 5.29safe
- Accruals / assets
- −12.5%clean
- Piotroski F-Score
- 5/9mixed
Altman Z″is a textbook bankruptcy-distress score from book values only (>2.6 safe · 1.1–2.6 grey · <1.1 distress). Accruals = (net income − operating cash flow) ÷ assets; persistently high accruals are an earnings-quality red flag. Beneish M-Scoreis an eight-ratio screen comparing this year with last (M > −1.78 = elevated manipulation-risk screen, not proof). Piotroski F-Scorecounts how many of nine fundamental-health checks pass (shown as passed / applicable; we use operating margin and total liabilities as documented proxies where the exact input isn't XBRL-tagged). Computed from SEC filings — descriptive factors, not advice or a forecast.
Quality score
EDS ScoreOur own multi-factor score from free SEC data — profitability, growth, financial strength, earnings quality, and event/ownership catalysts. No market price and no licensed model: each axis is the share of source-backed checks it passes. Descriptive factors, not advice or a forecast.
Signs
● 2 warning● 5 good- Operating losses (negative operating margin)
- Reported a net loss
- Revenue is growing year-over-year
- Conservative leverage (liabilities < 50% of assets)
- Positive operating cash flow
- Clean earnings (low accruals)
- Altman Z″ in the safe zone
Derived from the company's own SEC figures (fundamentals, forensic scores, filing discipline) — descriptive factors, not advice or a forecast.
Clinical trials
ClinicalTrials.gov · ongoing · next readout first- Phase 3Recruitingreadout ~2027-03A Double-blind Study Evaluating the Efficacy, Safety, and Tolerability of Zorevunersen in Patients With Dravet Syndrome
- Phase 2Active Not Recruitingreadout ~2029-03-31An Open-Label Extension Study of STK-001 for Patients With Dravet Syndrome
Interventional studies led by this company. “Readout” is the trial's primary-completion date — an estimate the sponsor reports, not a guarantee.
5%+ owners
SEC Schedule 13D / 13G · last 3 yrs- Lynx1 Capital Management LpPassive (13G)May 18, 2026
- Rtw Investments, LpPassive (13G)May 15, 2026
- Redmile Group, LlcPassive (13G)May 15, 2026
- Toronto Dominion BankPassive (13G)May 15, 2026
- Wellington Management Group LlpPassive (13G)May 15, 2026
- Vanguard Group IncPassive (13G)Mar 27, 2026
- Baker Bros. Advisors LpPassive (13G)Feb 17, 2026
- Fmr LlcPassive (13G)Feb 5, 2026
- Cowen Financial Products LlcPassive (13G)Nov 14, 2025
- Blackrock, Inc.Passive (13G)Oct 17, 2025
- Skorpios TrustActivist (13D)Aug 26, 2025
- Blackrock Portfolio Management LlcPassive (13G)Jul 15, 2025
Holders who disclosed a 5%+ stake. 13D signals intent to influence or control; 13G is a passive holding. Latest filing per holder — open it for the exact stake.
Short interest
FINRA · bi-monthly| Settlement | Shares short | Days to cover | Δ vs prior |
|---|---|---|---|
| May 15, 2026 | 12.9M | 24.8 | -0.8% |
| Apr 30, 2026 | 13.0M | 27.0 | +3.9% |
| Apr 15, 2026 | 12.5M | 20.8 | -2.2% |
| Mar 31, 2026 | 12.8M | 12.6 | -4.2% |
| Mar 13, 2026 | 13.4M | 14.5 | +7.9% |
Shares sold short as reported to FINRA. Days-to-cover = short shares ÷ average daily volume — higher means more potential squeeze pressure.
Material events
SEC Form 8-K · most recent- Results of operationsMay 7, 2026
- Director / officer change · Regulation FD disclosureApr 7, 2026
- Changed auditorMar 27, 2026
- Director / officer changeMar 3, 2026
- Entered a material agreement · New financial obligationJan 26, 2026
- Results of operations · Regulation FD disclosure · Other material eventJan 12, 2026
- Regulation FD disclosure · Other material eventDec 5, 2025
- Results of operationsNov 4, 2025
Events the company reported on Form 8-K, labelled by the SEC item code it filed under — its own classification, not our interpretation.
Recent SEC filings
All filings ↗- SCHEDULE 13G/AMay 18, 2026
- SCHEDULE 13G/AMay 15, 2026
- SCHEDULE 13G/AMay 15, 2026
- SCHEDULE 13G/AMay 15, 2026
- SCHEDULE 13G/AMay 15, 2026
- SCHEDULE 13GMay 15, 2026
- 8-KMay 7, 2026
- 10-QMay 7, 2026
- 4May 5, 2026
- 144May 1, 2026
- ARSApr 22, 2026
- DEFA14AApr 22, 2026
- DEF 14AApr 22, 2026
- 4Apr 7, 2026
- 3Apr 7, 2026