Q32 Bio Inc.
QTTBNasdaqHealthcare · Pharmaceutical Preparations · DE · SEC filings ↗ · Compare ⊕
View price & chart on Yahoo Finance ↗Financials
SEC XBRL · annual| FY25 | FY24 | FY23 | FY22 | FY21 | FY20 | |
|---|---|---|---|---|---|---|
| Revenue | $53.7M | $0 | $1.2M | $3.2M | $34.0M | $2.7M |
| Operating income | $16.9M | −$66.1M | −$48.3M | −$133.3M | −$95.9M | −$130.3M |
| Net income | $29.8M | −$47.7M | −$53.7M | −$5.0M | −$95.8M | −$128.7M |
| Total assets | $61.8M | $92.3M | $47.1M | $228.5M | $211.7M | $263.7M |
| Total liabilities | $19.8M | $86.7M | $118.5M | $50.5M | $42.1M | $67.7M |
| Equity | $42.0M | $5.7M | −$182.9M | −$130.7M | $169.7M | $196.0M |
| EPS (diluted) | $2.42 | $-6.58 | $-153.96 | $-0.09 | $-1.73 | — |
| Shares out. | 12.2M | 58.1M | 57.7M | 57.4M | 50.5M | 45.2M |
Reported figures from the company's SEC filings (XBRL). Blank where a line item isn't cleanly tagged — never estimated.
Key ratios
from filings · FY2025- Operating margin
- 31.5%
- Net margin
- 55.5%
- Return on equity
- 71.0%
- Return on assets
- 48.3%
- Return on capital (ROCE)
- 33.5%
- Liabilities / assets
- 32.0%
- Debt / equity
- 0.47×
- Book value / share
- $3.44
- Revenue growth (YoY)
- —
- Net income growth (YoY)
- —
Computed from the company's own SEC figures — no market price, so these are facts, not a valuation. Book value per share is reported equity ÷ shares; it is not the stock price.
Financial health
forensic scores · FY2025- Altman Z″ (distress)
- -2.11distress
- Accruals / assets
- 102.6%high accruals
- Piotroski F-Score
- 5/8mixed
Altman Z″is a textbook bankruptcy-distress score from book values only (>2.6 safe · 1.1–2.6 grey · <1.1 distress). Accruals = (net income − operating cash flow) ÷ assets; persistently high accruals are an earnings-quality red flag. Beneish M-Scoreis an eight-ratio screen comparing this year with last (M > −1.78 = elevated manipulation-risk screen, not proof). Piotroski F-Scorecounts how many of nine fundamental-health checks pass (shown as passed / applicable; we use operating margin and total liabilities as documented proxies where the exact input isn't XBRL-tagged). Computed from SEC filings — descriptive factors, not advice or a forecast.
Quality score
EDS ScoreOur own multi-factor score from free SEC data — profitability, growth, financial strength, earnings quality, and event/ownership catalysts. No market price and no licensed model: each axis is the share of source-backed checks it passes. Descriptive factors, not advice or a forecast.
Signs
● 1 severe● 2 warning● 3 good- Altman Z″ in the distress zone
- Negative operating cash flow
- High accruals — earnings-quality risk
- Operating margin is positive
- Strong return on equity (>15%)
- Conservative leverage (liabilities < 50% of assets)
Derived from the company's own SEC figures (fundamentals, forensic scores, filing discipline) — descriptive factors, not advice or a forecast.
Clinical trials
ClinicalTrials.gov · ongoing · next readout first- Phase 2Active Not Recruitingreadout ~2024-12Evaluating Safety and Efficacy of ADX-914 in Patients With Moderate to Severe Atopic Dermatitis (SIGNAL-AD)
- Phase 2Active Not Recruitingreadout ~2026-06A Phase 2a Proof-of-Concept Trial of Bempikibart (ADX-914) for the Treatment of Severe Alopecia Areata (SIGNAL-AA)
Interventional studies led by this company. “Readout” is the trial's primary-completion date — an estimate the sponsor reports, not a guarantee.
5%+ owners
SEC Schedule 13D / 13G · last 3 yrs- Atlas Venture Fund X, L.P.Activist (13D)May 28, 2026
- Point72 Asset Management, L.P.Passive (13G)May 15, 2026
- Sirenia Capital Management LpPassive (13G)May 15, 2026
- Opaleye Management Inc.Passive (13G)May 6, 2026
- Orbimed Advisors LlcActivist (13D)May 6, 2026
- Pfizer IncPassive (13G)Feb 13, 2026
- Sio Capital Management, LlcPassive (13G)Apr 8, 2025
- Bristol Myers Squibb CoPassive (13G)Feb 14, 2025
- Adar1 Partners, LpPassive (13G)Mar 14, 2024
Holders who disclosed a 5%+ stake. 13D signals intent to influence or control; 13G is a passive holding. Latest filing per holder — open it for the exact stake.
Insider transactions
SEC Form 4 · most recent| Insider | Date | Type | Shares | Price |
|---|---|---|---|---|
| Violette Shelia M.Officer — Chief Scientific Officer | Feb 24, 2026 | Grant | 37,500 | $0.00 |
| Morrison Jodie PopeOfficer — CEO | Feb 24, 2026 | Grant | 132,000 | $0.00 |
| Kalowski LeeOfficer — CFO and President | Feb 24, 2026 | Grant | 53,250 | $0.00 |
| Kalowski LeeOfficer — CFO and President | Feb 25, 2026 | Sell | 3,995 | $4.51 |
| Morrison Jodie PopeOfficer — CEO | Feb 25, 2026 | Sell | 9,896 | $4.51 |
| Violette Shelia M.Officer — Chief Scientific Officer | Feb 25, 2026 | Sell | 2,815 | $4.51 |
| Morrison Jodie PopeOfficer — CEO | Dec 2, 2025 | Sell | 22,506 | $3.46 |
| Kalowski LeeOfficer — CFO and President | Dec 2, 2025 | Sell | 9,072 | $3.46 |
Headline trade per Form 4 (officers, directors, 10%+ owners). Buy/sell read from the filing's structured data — blank where a field isn't cleanly tagged.
Short interest
FINRA · bi-monthly| Settlement | Shares short | Days to cover | Δ vs prior |
|---|---|---|---|
| May 15, 2026 | 632,722 | 2.7 | -3.1% |
| Apr 30, 2026 | 652,815 | 1.6 | +70.7% |
| Apr 15, 2026 | 382,350 | 1.2 | -7.0% |
| Mar 31, 2026 | 411,011 | 1.2 | +17.3% |
| Mar 13, 2026 | 350,520 | 1.1 | -3.2% |
Shares sold short as reported to FINRA. Days-to-cover = short shares ÷ average daily volume — higher means more potential squeeze pressure.
Material events
SEC Form 8-K · most recent- Entered a material agreement · Unregistered equity sale · Other material eventMay 27, 2026
- Results of operationsMay 5, 2026
- Other material eventApr 24, 2026
- Entered a material agreementMar 27, 2026
- Results of operationsMar 10, 2026
- Entered a material agreement · Other material eventFeb 17, 2026
- Director / officer changeDec 19, 2025
- Entered a material agreement · Terminated a material agreement · Completed an acquisition or disposition · Regulation FD disclosure · Other material eventDec 1, 2025
Events the company reported on Form 8-K, labelled by the SEC item code it filed under — its own classification, not our interpretation.
Recent SEC filings
All filings ↗- SCHEDULE 13D/AMay 28, 2026
- 8-KMay 27, 2026
- SCHEDULE 13G/AMay 15, 2026
- SCHEDULE 13GMay 15, 2026
- SCHEDULE 13D/AMay 6, 2026
- SCHEDULE 13G/AMay 6, 2026
- 10-QMay 5, 2026
- 8-KMay 5, 2026
- ARSApr 30, 2026
- DEFA14AApr 30, 2026
- DEF 14AApr 30, 2026
- 8-KApr 24, 2026
- 424B5Apr 24, 2026
- 8-KMar 27, 2026
- 424B5Mar 27, 2026