Prelude Therapeutics Inc
PRLDNasdaqHealthcare · Pharmaceutical Preparations · DE · SEC filings ↗ · Compare ⊕
View price & chart on Yahoo Finance ↗Financials
SEC XBRL · annual| FY25 | FY24 | FY23 | FY22 | FY21 | FY20 | |
|---|---|---|---|---|---|---|
| Revenue | $12.1M | $7.0M | — | — | — | — |
| Operating income | −$104.6M | −$139.7M | −$132.3M | −$123.5M | −$113.7M | −$58.8M |
| Net income | −$99.5M | −$127.2M | −$121.8M | −$115.4M | −$111.7M | −$56.9M |
| Total assets | $141.3M | $175.5M | $277.7M | $220.5M | $305.1M | $223.6M |
| Total liabilities | $72.7M | $44.1M | $40.6M | $25.1M | $19.2M | $11.4M |
| Equity | $68.6M | $131.5M | $237.1M | $195.4M | $285.9M | $212.2M |
| EPS (diluted) | $-1.29 | $-1.68 | $-2.02 | $-2.44 | $-2.43 | — |
| Shares out. | 55.2M | 54.9M | 47.9M | 47.6M | 46.6M | — |
Reported figures from the company's SEC filings (XBRL). Blank where a line item isn't cleanly tagged — never estimated.
Key ratios
from filings · FY2025- Operating margin
- −861.3%
- Net margin
- −819.6%
- Return on equity
- −145.0%
- Return on assets
- −70.4%
- Return on capital (ROCE)
- −118.4%
- Liabilities / assets
- 51.4%
- Debt / equity
- 1.06×
- Book value / share
- $1.24
- Revenue growth (YoY)
- 73.4%
- Net income growth (YoY)
- —
Computed from the company's own SEC figures — no market price, so these are facts, not a valuation. Book value per share is reported equity ÷ shares; it is not the stock price.
Financial health
forensic scores · FY2025- Altman Z″ (distress)
- -17.29distress
- Accruals / assets
- −30.6%clean
- Piotroski F-Score
- 4/9mixed
Altman Z″is a textbook bankruptcy-distress score from book values only (>2.6 safe · 1.1–2.6 grey · <1.1 distress). Accruals = (net income − operating cash flow) ÷ assets; persistently high accruals are an earnings-quality red flag. Beneish M-Scoreis an eight-ratio screen comparing this year with last (M > −1.78 = elevated manipulation-risk screen, not proof). Piotroski F-Scorecounts how many of nine fundamental-health checks pass (shown as passed / applicable; we use operating margin and total liabilities as documented proxies where the exact input isn't XBRL-tagged). Computed from SEC filings — descriptive factors, not advice or a forecast.
Quality score
EDS ScoreOur own multi-factor score from free SEC data — profitability, growth, financial strength, earnings quality, and event/ownership catalysts. No market price and no licensed model: each axis is the share of source-backed checks it passes. Descriptive factors, not advice or a forecast.
Signs
● 1 severe● 3 warning● 2 good- Altman Z″ in the distress zone
- Operating losses (negative operating margin)
- Reported a net loss
- Negative operating cash flow
- Revenue is growing year-over-year
- Clean earnings (low accruals)
Derived from the company's own SEC figures (fundamentals, forensic scores, filing discipline) — descriptive factors, not advice or a forecast.
Clinical trials
ClinicalTrials.gov · ongoing · next readout firstInterventional studies led by this company. “Readout” is the trial's primary-completion date — an estimate the sponsor reports, not a guarantee.
5%+ owners
SEC Schedule 13D / 13G · last 3 yrs- Ra Capital Management, L.P.Passive (13G)Apr 28, 2026
- Orbimed Advisors LlcActivist (13D)Apr 23, 2026
- Baker Bros. Advisors LpActivist (13D)Apr 22, 2026
- Vaddi KrishnaPassive (13G)Feb 13, 2026
- Incyte CorpPassive (13G)Nov 7, 2025
- Flynn James EPassive (13G)Feb 13, 2025
Holders who disclosed a 5%+ stake. 13D signals intent to influence or control; 13G is a passive holding. Latest filing per holder — open it for the exact stake.
Short interest
FINRA · bi-monthly| Settlement | Shares short | Days to cover | Δ vs prior |
|---|---|---|---|
| May 15, 2026 | 1.9M | 3.5 | +19.1% |
| Apr 30, 2026 | 1.6M | 2.7 | -14.0% |
| Apr 15, 2026 | 1.8M | 5.2 | -22.1% |
| Mar 31, 2026 | 2.3M | 13.8 | +1.9% |
| Mar 13, 2026 | 2.3M | 8.1 | +0.1% |
Shares sold short as reported to FINRA. Days-to-cover = short shares ÷ average daily volume — higher means more potential squeeze pressure.
Material events
SEC Form 8-K · most recent- Results of operations · Regulation FD disclosureMay 12, 2026
- Entered a material agreement · Other material eventApr 21, 2026
- Regulation FD disclosure · Other material eventApr 20, 2026
- Director / officer changeApr 15, 2026
- Other material eventMar 12, 2026
- Results of operations · Regulation FD disclosureMar 10, 2026
- Regulation FD disclosureFeb 3, 2026
- Regulation FD disclosureJan 9, 2026
Events the company reported on Form 8-K, labelled by the SEC item code it filed under — its own classification, not our interpretation.
Recent SEC filings
All filings ↗- 10-QMay 12, 2026
- 8-KMay 12, 2026
- 4PRIMARY DOCUMENTMay 4, 2026
- ARSApr 29, 2026
- DEFA14AApr 29, 2026
- DEF 14AApr 29, 2026
- SCHEDULE 13GApr 28, 2026
- 4Apr 28, 2026
- 3Apr 28, 2026
- SCHEDULE 13D/AApr 23, 2026
- 4Apr 23, 2026
- 4Apr 23, 2026
- SCHEDULE 13D/AApr 22, 2026
- 4Apr 22, 2026
- 8-KApr 21, 2026
Event-driven situations (2)
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