Inozyme Pharma, Inc.
INZYHealthcare · Pharmaceutical Preparations · DE · SEC filings ↗ · Compare ⊕
View price & chart on Yahoo Finance ↗Financials
SEC XBRL · annual| FY24 | FY23 | FY22 | FY21 | FY20 | FY19 | |
|---|---|---|---|---|---|---|
| Revenue | — | — | — | — | — | — |
| Operating income | −$104.0M | −$75.6M | −$68.7M | −$56.6M | −$57.0M | −$20.8M |
| Net income | −$102.0M | −$71.2M | −$67.1M | −$56.6M | −$56.4M | −$19.7M |
| Total assets | $123.2M | $200.8M | $139.2M | $123.5M | $169.4M | $47.9M |
| Total liabilities | $65.4M | $60.4M | $20.8M | $14.3M | $11.3M | $3.2M |
| Equity | $57.8M | $140.5M | $118.4M | $109.3M | $158.1M | −$33.2M |
| EPS (diluted) | $-1.62 | $-1.37 | $-1.78 | $-2.40 | — | — |
| Shares out. | 64.2M | 43.7M | 23.7M | 23.5M | 23.4M | 1.2M |
Reported figures from the company's SEC filings (XBRL). Blank where a line item isn't cleanly tagged — never estimated.
Key ratios
from filings · FY2024- Operating margin
- —
- Net margin
- —
- Return on equity
- −176.4%
- Return on assets
- −82.8%
- Return on capital (ROCE)
- −116.5%
- Liabilities / assets
- 53.1%
- Debt / equity
- 1.13×
- Book value / share
- $0.90
- Revenue growth (YoY)
- —
- Net income growth (YoY)
- —
Computed from the company's own SEC figures — no market price, so these are facts, not a valuation. Book value per share is reported equity ÷ shares; it is not the stock price.
Financial health
forensic scores · FY2024- Altman Z″ (distress)
- -10.39distress
- Accruals / assets
- −8.2%clean
- Piotroski F-Score
- 1/7weak
Altman Z″is a textbook bankruptcy-distress score from book values only (>2.6 safe · 1.1–2.6 grey · <1.1 distress). Accruals = (net income − operating cash flow) ÷ assets; persistently high accruals are an earnings-quality red flag. Beneish M-Scoreis an eight-ratio screen comparing this year with last (M > −1.78 = elevated manipulation-risk screen, not proof). Piotroski F-Scorecounts how many of nine fundamental-health checks pass (shown as passed / applicable; we use operating margin and total liabilities as documented proxies where the exact input isn't XBRL-tagged). Computed from SEC filings — descriptive factors, not advice or a forecast.
Quality score
EDS ScoreOur own multi-factor score from free SEC data — profitability, growth, financial strength, earnings quality, and event/ownership catalysts. No market price and no licensed model: each axis is the share of source-backed checks it passes. Descriptive factors, not advice or a forecast.
Signs
● 1 severe● 1 warning● 1 good- Altman Z″ in the distress zone
- Negative operating cash flow
- Clean earnings (low accruals)
Derived from the company's own SEC figures (fundamentals, forensic scores, filing discipline) — descriptive factors, not advice or a forecast.
Clinical trials
ClinicalTrials.gov · ongoing · next readout first- Phase 3Active Not Recruitingreadout ~2026-01The ENERGY 3 Study: Evaluation of Efficacy and Safety of INZ-701 in Children With ENPP1 Deficiency
- Phase 1Recruitingreadout ~2027-11-11The ENERGY Study: Evaluation of Safety and Tolerability of INZ-701 in Infants With ENPP1 Deficiency or ABCC6 Deficiency
- Phase 3Recruitingreadout ~2028-09-11ENERGY 2: Evaluation of the Efficacy and Safety of INZ-701 in Infants With ENPP1 Deficiency
- Phase 2Recruitingreadout ~2030-11ADAPT Study: Long-term Safety Study of INZ-701 in Patients With ENPP1 Deficiency and ABCC6 Deficiency
Interventional studies led by this company. “Readout” is the trial's primary-completion date — an estimate the sponsor reports, not a guarantee.
5%+ owners
SEC Schedule 13D / 13G · last 3 yrs- Pivotal Bioventure Partners Fund I, L.P.Activist (13D)Aug 27, 2025
- Beryl Capital Management LlcPassive (13G)Aug 14, 2025
- Rock Springs Capital Management LpPassive (13G)Aug 13, 2025
- Adage Capital Management, L.P.Passive (13G)Aug 12, 2025
- Blackrock, Inc.Passive (13G)Jul 17, 2025
- Glazer Capital, LlcPassive (13G)Jun 4, 2025
- Affinity Asset Advisors, LlcPassive (13G)May 30, 2025
- Eventide Asset Management, LlcPassive (13G)Apr 23, 2025
- Samlyn Capital, LlcPassive (13G)Feb 14, 2025
Holders who disclosed a 5%+ stake. 13D signals intent to influence or control; 13G is a passive holding. Latest filing per holder — open it for the exact stake.
Short interest
FINRA · bi-monthly| Settlement | Shares short | Days to cover | Δ vs prior |
|---|---|---|---|
| Jun 30, 2025 | 1.5M | 1.2 | -55.0% |
| Jun 13, 2025 | 3.4M | 3.8 | -8.0% |
| May 30, 2025 | 3.7M | 1.0 | -4.1% |
| May 15, 2025 | 3.8M | 1.7 | -3.7% |
| Apr 30, 2025 | 4.0M | 9.1 | -9.9% |
Shares sold short as reported to FINRA. Days-to-cover = short shares ÷ average daily volume — higher means more potential squeeze pressure.
Material events
SEC Form 8-K · most recent- Terminated a material agreement · Completed an acquisition or disposition · Delisting / listing-standard notice · Modified shareholder rights · Change in control · Director / officer change · Amended charter or bylawsJul 1, 2025
- Other material eventJun 23, 2025
- Director / officer changeJun 2, 2025
- Entered a material agreement · Regulation FD disclosureMay 16, 2025
- Completed an acquisition or dispositionMay 14, 2025
- Results of operations · Costs from exit or disposalMar 10, 2025
- Results of operations · Regulation FD disclosure · Other material eventJan 10, 2025
- Results of operationsNov 5, 2024
Events the company reported on Form 8-K, labelled by the SEC item code it filed under — its own classification, not our interpretation.
Recent SEC filings
All filings ↗- SCHEDULE 13D/AAug 27, 2025
- SCHEDULE 13G/AAug 14, 2025
- SCHEDULE 13G/AAug 13, 2025
- SCHEDULE 13G/AAug 12, 2025
- SCHEDULE 13G/AJul 17, 2025
- 15-12GJul 11, 2025
- 4Jul 3, 2025
- 4Jul 3, 2025
- 4Jul 3, 2025
- 4Jul 3, 2025
- 4Jul 3, 2025
- 4Jul 3, 2025
- EFFECTJul 1, 2025
- EFFECTJul 1, 2025
- 25-NSEJul 1, 2025