Lyell Immunopharma, Inc.
LYELNasdaqHealthcare · Pharmaceutical Preparations · DE · SEC filings ↗ · Compare ⊕
View price & chart on Yahoo Finance ↗Financials
SEC XBRL · annual| FY25 | FY24 | FY23 | FY22 | FY21 | FY20 | |
|---|---|---|---|---|---|---|
| Revenue | $36,000 | $61,000 | $130,000 | $84.7M | $10.7M | $7.8M |
| Operating income | −$269.4M | −$358.8M | −$247.0M | −$187.1M | −$214.8M | −$211.9M |
| Net income | −$274.4M | −$343.0M | −$234.6M | −$183.1M | −$250.2M | −$204.5M |
| Total assets | $340.1M | $490.9M | $750.0M | $937.6M | $1.13B | $908.3M |
| Total liabilities | $91.8M | $108.0M | $95.1M | $104.3M | $197.6M | $189.8M |
| Equity | $248.2M | $382.8M | $655.0M | $833.3M | $929.8M | −$292.5M |
| EPS (diluted) | $-16.06 | $-26.23 | $-18.70 | $-0.74 | $-1.84 | $-15.69 |
| Shares out. | 295.2M | 254.1M | 249.6M | 245.4M | 242.7M | 15.6M |
Reported figures from the company's SEC filings (XBRL). Blank where a line item isn't cleanly tagged — never estimated.
Key ratios
from filings · FY2025- Operating margin
- −748344.4%
- Net margin
- −762355.6%
- Return on equity
- −110.6%
- Return on assets
- −80.7%
- Return on capital (ROCE)
- −92.7%
- Liabilities / assets
- 27.0%
- Debt / equity
- 0.37×
- Book value / share
- $0.84
- Revenue growth (YoY)
- −41.0%
- Net income growth (YoY)
- —
Computed from the company's own SEC figures — no market price, so these are facts, not a valuation. Book value per share is reported equity ÷ shares; it is not the stock price.
Financial health
forensic scores · FY2025- Altman Z″ (distress)
- -13.93distress
- Accruals / assets
- −36.6%clean
- Piotroski F-Score
- 1/9weak
Altman Z″is a textbook bankruptcy-distress score from book values only (>2.6 safe · 1.1–2.6 grey · <1.1 distress). Accruals = (net income − operating cash flow) ÷ assets; persistently high accruals are an earnings-quality red flag. Beneish M-Scoreis an eight-ratio screen comparing this year with last (M > −1.78 = elevated manipulation-risk screen, not proof). Piotroski F-Scorecounts how many of nine fundamental-health checks pass (shown as passed / applicable; we use operating margin and total liabilities as documented proxies where the exact input isn't XBRL-tagged). Computed from SEC filings — descriptive factors, not advice or a forecast.
Quality score
EDS ScoreOur own multi-factor score from free SEC data — profitability, growth, financial strength, earnings quality, and event/ownership catalysts. No market price and no licensed model: each axis is the share of source-backed checks it passes. Descriptive factors, not advice or a forecast.
Signs
● 1 severe● 4 warning● 2 good- Altman Z″ in the distress zone
- Operating losses (negative operating margin)
- Reported a net loss
- Revenue declined year-over-year
- Negative operating cash flow
- Conservative leverage (liabilities < 50% of assets)
- Clean earnings (low accruals)
Derived from the company's own SEC figures (fundamentals, forensic scores, filing discipline) — descriptive factors, not advice or a forecast.
Clinical trials
ClinicalTrials.gov · ongoing · next readout first- Phase 1Recruitingreadout ~2028-06GCC19CART for Patients With Metastatic Colorectal Cancer
- Phase 1/2Recruitingreadout ~2028-12-31Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma
- Phase 3Recruitingreadout ~2029-12A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy
Interventional studies led by this company. “Readout” is the trial's primary-completion date — an estimate the sponsor reports, not a guarantee.
5%+ owners
SEC Schedule 13D / 13G · last 3 yrs- Arch Venture Fund Ix, L.P.Passive (13G)May 15, 2026
- Mwg Caph LtdPassive (13G)May 11, 2026
- Explore Investments Llc/DePassive (13G)May 8, 2026
- Euler Fund, L.P.Passive (13G)Apr 21, 2026
- Foresite Capital Fund Iv, L.P.Passive (13G)Nov 14, 2025
- Innovative Cellular Therapeutics Holdings LtdPassive (13G)Nov 13, 2025
- Newton (Ptc) LtdPassive (13G)Nov 12, 2025
- Gates Frontier, LlcPassive (13G)Aug 1, 2025
- Blackrock, Inc.Passive (13G)Feb 5, 2025
Holders who disclosed a 5%+ stake. 13D signals intent to influence or control; 13G is a passive holding. Latest filing per holder — open it for the exact stake.
Short interest
FINRA · bi-monthly| Settlement | Shares short | Days to cover | Δ vs prior |
|---|---|---|---|
| May 15, 2026 | 1.3M | 23.3 | -0.3% |
| Apr 30, 2026 | 1.3M | 18.8 | +8.9% |
| Apr 15, 2026 | 1.2M | 12.0 | +8.4% |
| Mar 31, 2026 | 1.1M | 12.8 | +21.1% |
| Mar 13, 2026 | 940,269 | 8.6 | +15.3% |
Shares sold short as reported to FINRA. Days-to-cover = short shares ÷ average daily volume — higher means more potential squeeze pressure.
Material events
SEC Form 8-K · most recent- Results of operationsMay 6, 2026
- Results of operationsMar 12, 2026
- Director / officer changeMar 9, 2026
- Other material eventDec 8, 2025
- Amended charter or bylawsDec 5, 2025
- Results of operationsNov 12, 2025
- Entered a material agreement · Unregistered equity sale · Regulation FD disclosureNov 10, 2025
- Director / officer changeNov 3, 2025
Events the company reported on Form 8-K, labelled by the SEC item code it filed under — its own classification, not our interpretation.
Recent SEC filings
All filings ↗- SCHEDULE 13G/AMay 15, 2026
- SCHEDULE 13G/AMay 11, 2026
- SCHEDULE 13G/AMay 8, 2026
- 10-QMay 6, 2026
- 8-KMay 6, 2026
- ARSApr 24, 2026
- DEFA14AApr 24, 2026
- DEF 14AApr 24, 2026
- SCHEDULE 13GApr 21, 2026
- EFFECTApr 14, 2026
- CORRESPApr 13, 2026
- UPLOADApr 8, 2026
- S-3Apr 3, 2026
- 4Mar 16, 2026
- 3Mar 16, 2026