ALX ONCOLOGY HOLDINGS INC
ALXONasdaqHealthcare · Pharmaceutical Preparations · DE · SEC filings ↗ · Compare ⊕
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SEC XBRL · annual| FY25 | FY24 | FY23 | FY22 | FY21 | FY20 | |
|---|---|---|---|---|---|---|
| Revenue | — | — | — | $0 | $0 | $1.2M |
| Operating income | −$104.0M | −$142.5M | −$170.3M | −$127.4M | −$83.6M | −$43.7M |
| Net income | −$101.7M | −$134.8M | −$160.8M | −$123.5M | −$83.5M | −$45.7M |
| Total assets | $59.0M | $147.8M | $242.6M | $306.5M | $380.2M | $436.1M |
| Total liabilities | $33.1M | $34.2M | $52.8M | $43.0M | $17.1M | $6.2M |
| Equity | $26.0M | $113.6M | $189.7M | $263.5M | $363.0M | $429.8M |
| EPS (diluted) | $-1.90 | $-2.58 | $-3.74 | $-3.03 | $-2.07 | $-2.76 |
| Shares out. | 53.4M | 50.2M | 40.9M | 40.6M | 40.1M | 39.8M |
Reported figures from the company's SEC filings (XBRL). Blank where a line item isn't cleanly tagged — never estimated.
Key ratios
from filings · FY2025- Operating margin
- —
- Net margin
- —
- Return on equity
- −391.4%
- Return on assets
- −172.2%
- Return on capital (ROCE)
- −301.6%
- Liabilities / assets
- 56.0%
- Debt / equity
- 1.27×
- Book value / share
- $0.49
- Revenue growth (YoY)
- —
- Net income growth (YoY)
- —
Computed from the company's own SEC figures — no market price, so these are facts, not a valuation. Book value per share is reported equity ÷ shares; it is not the stock price.
Financial health
forensic scores · FY2025- Altman Z″ (distress)
- -48.01distress
- Accruals / assets
- −29.7%clean
- Piotroski F-Score
- 1/7weak
Altman Z″is a textbook bankruptcy-distress score from book values only (>2.6 safe · 1.1–2.6 grey · <1.1 distress). Accruals = (net income − operating cash flow) ÷ assets; persistently high accruals are an earnings-quality red flag. Beneish M-Scoreis an eight-ratio screen comparing this year with last (M > −1.78 = elevated manipulation-risk screen, not proof). Piotroski F-Scorecounts how many of nine fundamental-health checks pass (shown as passed / applicable; we use operating margin and total liabilities as documented proxies where the exact input isn't XBRL-tagged). Computed from SEC filings — descriptive factors, not advice or a forecast.
Quality score
EDS ScoreOur own multi-factor score from free SEC data — profitability, growth, financial strength, earnings quality, and event/ownership catalysts. No market price and no licensed model: each axis is the share of source-backed checks it passes. Descriptive factors, not advice or a forecast.
Signs
● 1 severe● 1 warning● 1 good- Altman Z″ in the distress zone
- Negative operating cash flow
- Clean earnings (low accruals)
Derived from the company's own SEC figures (fundamentals, forensic scores, filing discipline) — descriptive factors, not advice or a forecast.
Clinical trials
ClinicalTrials.gov · ongoing · next readout first- Phase 2/3Active Not Recruitingreadout ~2024-05-24A Study of Evorpacept (ALX148) in Patients With Advanced HER2+ Gastric Cancer (ASPEN-06)
- Phase 2Active Not Recruitingreadout ~2025-03-03Evorpacept (ALX148) in Combination With Pembrolizumab and Chemotherapy in Patients With Advanced Head and Neck Squamous Cell Carcinoma (ASPEN-04)
- Phase 2Active Not Recruitingreadout ~2025-03-03Evorpacept (ALX148) in Combination With Pembrolizumab in Patients With Advanced Head and Neck Squamous Cell Carcinoma (ASPEN-03)
- Phase 1Recruitingreadout ~2027-06A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors
- Phase 2Recruitingreadout ~2027-12ASPEN-09-03: A Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Metastatic HER2-Positive Breast Cancer
Interventional studies led by this company. “Readout” is the trial's primary-completion date — an estimate the sponsor reports, not a guarantee.
5%+ owners
SEC Schedule 13D / 13G · last 3 yrs- Lsv Associates, LlcActivist (13D)May 27, 2026
- Redmile Group, LlcPassive (13G)May 15, 2026
- Hbm Healthcare Investments (Cayman) Ltd.Passive (13G)May 15, 2026
- Millennium Management LlcPassive (13G)Apr 28, 2026
- Ra Capital Management, L.P.Passive (13G)Feb 9, 2026
- Tcg Crossover Gp Ii, LlcPassive (13G)Feb 6, 2026
- Venbio Global Strategic Fund, L.P.Activist (13D)Feb 4, 2026
- Tang Capital Management LlcPassive (13G)Nov 14, 2025
- Tang Capital Partners LpPassive (13G)Feb 14, 2025
- Fmr LlcPassive (13G)Dec 6, 2024
Holders who disclosed a 5%+ stake. 13D signals intent to influence or control; 13G is a passive holding. Latest filing per holder — open it for the exact stake.
Insider transactions
SEC Form 4 · most recent| Insider | Date | Type | Shares | Price |
|---|---|---|---|---|
| Lettmann JasonOfficer — CHIEF EXECUTIVE OFFICER | Mar 19, 2026 | Sell | 12,311 | $2.17 |
| Pinto ShellyOfficer — SVP, FINANCE AND CAO | Mar 19, 2026 | Sell | 903 | $2.17 |
| Pinto ShellyOfficer — SVP, FINANCE AND CAO | Feb 18, 2026 | Sell | 565 | $2.27 |
| Lettmann JasonOfficer — CHIEF EXECUTIVE OFFICER | Feb 17, 2026 | Tax withholding | 2,201 | $2.27 |
| Goodman Corey SDirector | Feb 2, 2026 | Buy | 3.2M | $1.57 |
Headline trade per Form 4 (officers, directors, 10%+ owners). Buy/sell read from the filing's structured data — blank where a field isn't cleanly tagged.
Short interest
FINRA · bi-monthly| Settlement | Shares short | Days to cover | Δ vs prior |
|---|---|---|---|
| May 15, 2026 | 1.4M | 1.9 | -37.5% |
| Apr 30, 2026 | 2.2M | 1.9 | +7.9% |
| Apr 15, 2026 | 2.0M | 1.7 | -8.0% |
| Mar 31, 2026 | 2.2M | 2.9 | +81.7% |
| Mar 13, 2026 | 1.2M | 2.4 | +4.3% |
Shares sold short as reported to FINRA. Days-to-cover = short shares ÷ average daily volume — higher means more potential squeeze pressure.
Material events
SEC Form 8-K · most recent- Results of operationsMay 8, 2026
- Director / officer change · Regulation FD disclosureApr 13, 2026
- Results of operationsFeb 27, 2026
- Entered a material agreement · Other material eventJan 30, 2026
- Other material eventJan 30, 2026
- Director / officer changeJan 21, 2026
- Results of operationsNov 7, 2025
- Director / officer change · Other material eventSep 12, 2025
Events the company reported on Form 8-K, labelled by the SEC item code it filed under — its own classification, not our interpretation.
Recent SEC filings
All filings ↗- SCHEDULE 13D/AMay 27, 2026
- SCHEDULE 13G/AMay 15, 2026
- SCHEDULE 13G/AMay 15, 2026
- 10-QMay 8, 2026
- 8-KMay 8, 2026
- SCHEDULE 13G/AApr 28, 2026
- ARSApr 20, 2026
- DEF 14AApr 20, 2026
- 4Apr 17, 2026
- 4Apr 17, 2026
- 3Apr 17, 2026
- 8-KApr 13, 2026
- 4Mar 23, 2026
- 4Mar 23, 2026
- 10-KMar 9, 2026