Zymeworks Inc.
ZYMENasdaqHealthcare · Pharmaceutical Preparations · DE · SEC filings ↗ · Compare ⊕
View price & chart on Yahoo Finance ↗Financials
SEC XBRL · annual| FY25 | FY24 | FY23 | FY22 | FY21 | FY20 | |
|---|---|---|---|---|---|---|
| Revenue | $106.0M | $76.3M | $76.0M | $412.5M | $26.7M | $39.0M |
| Operating income | −$92.5M | −$137.1M | −$138.1M | $130.5M | −$215.6M | −$187.5M |
| Net income | −$81.1M | −$122.7M | −$118.7M | $124.3M | −$211.8M | −$180.6M |
| Total assets | $346.5M | $463.1M | $580.9M | $648.7M | $389.1M | — |
| Total liabilities | $78.0M | $124.3M | $116.1M | $155.8M | $140.0M | — |
| Equity | $268.5M | $338.8M | $464.8M | $493.0M | $249.1M | $409.9M |
| EPS (diluted) | $-1.08 | $-1.62 | $-1.72 | $1.90 | $-4.61 | $-3.58 |
| Shares out. | 69.6M | 70.6M | 64.0M | 63.1M | 46.6M | 50.4M |
Reported figures from the company's SEC filings (XBRL). Blank where a line item isn't cleanly tagged — never estimated.
Key ratios
from filings · FY2025- Operating margin
- −87.3%
- Net margin
- −76.6%
- Return on equity
- −30.2%
- Return on assets
- −23.4%
- Return on capital (ROCE)
- −30.4%
- Liabilities / assets
- 22.5%
- Debt / equity
- 0.29×
- Book value / share
- $3.86
- Revenue growth (YoY)
- 38.9%
- Net income growth (YoY)
- —
Computed from the company's own SEC figures — no market price, so these are facts, not a valuation. Book value per share is reported equity ÷ shares; it is not the stock price.
Financial health
forensic scores · FY2025- Altman Z″ (distress)
- -3.24distress
- Accruals / assets
- −13.9%clean
- Piotroski F-Score
- 7/9strong
Altman Z″is a textbook bankruptcy-distress score from book values only (>2.6 safe · 1.1–2.6 grey · <1.1 distress). Accruals = (net income − operating cash flow) ÷ assets; persistently high accruals are an earnings-quality red flag. Beneish M-Scoreis an eight-ratio screen comparing this year with last (M > −1.78 = elevated manipulation-risk screen, not proof). Piotroski F-Scorecounts how many of nine fundamental-health checks pass (shown as passed / applicable; we use operating margin and total liabilities as documented proxies where the exact input isn't XBRL-tagged). Computed from SEC filings — descriptive factors, not advice or a forecast.
Quality score
EDS ScoreOur own multi-factor score from free SEC data — profitability, growth, financial strength, earnings quality, and event/ownership catalysts. No market price and no licensed model: each axis is the share of source-backed checks it passes. Descriptive factors, not advice or a forecast.
Signs
● 1 severe● 3 warning● 3 good- Altman Z″ in the distress zone
- Operating losses (negative operating margin)
- Reported a net loss
- Negative operating cash flow
- Revenue is growing year-over-year
- Conservative leverage (liabilities < 50% of assets)
- Clean earnings (low accruals)
Derived from the company's own SEC figures (fundamentals, forensic scores, filing discipline) — descriptive factors, not advice or a forecast.
Clinical trials
ClinicalTrials.gov · ongoing · next readout first- Phase 1Active Not Recruitingreadout ~2026-12A Study of ZW191 in Participants With Solid Tumors
- Phase 1Recruitingreadout ~2027-09A Study of ZW251 in Participants With Advanced Solid Tumors
Interventional studies led by this company. “Readout” is the trial's primary-completion date — an estimate the sponsor reports, not a guarantee.
5%+ owners
SEC Schedule 13D / 13G · last 3 yrs- Rubric Capital Management LpPassive (13G)May 15, 2026
- Perceptive Advisors LlcPassive (13G)Apr 15, 2026
- Morgan StanleyPassive (13G)Feb 12, 2026
- Ecor1 Capital, LlcActivist (13D)Nov 19, 2025
- Redmile Group, LlcPassive (13G)Nov 14, 2025
- Biotechnology Value Fund L PPassive (13G)Nov 14, 2025
- Blackrock, Inc.Passive (13G)Jul 16, 2025
Holders who disclosed a 5%+ stake. 13D signals intent to influence or control; 13G is a passive holding. Latest filing per holder — open it for the exact stake.
Short interest
FINRA · bi-monthly| Settlement | Shares short | Days to cover | Δ vs prior |
|---|---|---|---|
| May 15, 2026 | 4.5M | 6.6 | -3.8% |
| Apr 30, 2026 | 4.6M | 8.4 | -0.1% |
| Apr 15, 2026 | 4.7M | 7.0 | +4.3% |
| Mar 31, 2026 | 4.5M | 8.1 | +9.4% |
| Mar 13, 2026 | 4.1M | 4.2 | -1.4% |
Shares sold short as reported to FINRA. Days-to-cover = short shares ÷ average daily volume — higher means more potential squeeze pressure.
Material events
SEC Form 8-K · most recent- Regulation FD disclosure · Other material eventMay 14, 2026
- Results of operations · Regulation FD disclosureMay 7, 2026
- Director / officer changeApr 1, 2026
- Entered a material agreement · New financial obligation · Regulation FD disclosureMar 2, 2026
- Results of operations · Regulation FD disclosureMar 2, 2026
- Results of operations · Director / officer change · Other material eventJan 12, 2026
- Shareholder voteDec 30, 2025
- Director / officer change · Regulation FD disclosure · Other material eventNov 18, 2025
Events the company reported on Form 8-K, labelled by the SEC item code it filed under — its own classification, not our interpretation.
Recent SEC filings
All filings ↗Event-driven situations (1)
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