Seaport Therapeutics, Inc.
SPTXNasdaqHealthcare · Pharmaceutical Preparations · DE · SEC filings ↗ · Compare ⊕
View price & chart on Yahoo Finance ↗Financials
SEC XBRL · annualNo structured XBRL financials available (common for pre-2009 filers, foreign issuers, or companies that never reported as a US public company).
Clinical trials
ClinicalTrials.gov · ongoing · next readout first- Phase 2Recruitingreadout ~2027-03A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)
- Phase 2Enrolling By Invitationreadout ~2027-05An Open-Label Extension Study to Evaluate the Safety and Tolerability of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 OLE Study)
Interventional studies led by this company. “Readout” is the trial's primary-completion date — an estimate the sponsor reports, not a guarantee.
Insider transactions
SEC Form 4 · most recent| Insider | Date | Type | Shares | Price |
|---|---|---|---|---|
| Puretech Health Plc10% owner | May 4, 2026 | Conversion | 12.7M | — |
| Healy JamesDirector | May 4, 2026 | Conversion | 1.9M | — |
| White LaurenOfficer — Chief Financial Officer | May 4, 2026 | Conversion | 6,702 | — |
| Gladstein LanaOfficer — General Counsel | May 4, 2026 | Conversion | 33,515 | — |
| Chen Michael CunyuanOfficer — Chief Scientific Officer | May 4, 2026 | Conversion | 3,351 | — |
| Torres DeniceDirector | May 4, 2026 | Conversion | 13,406 | — |
| Paul Steven MDirector | May 4, 2026 | Conversion | 67,031 | — |
| Arch Venture Partners Xii, Llc10% owner | May 4, 2026 | Conversion | 2.5M | — |
Headline trade per Form 4 (officers, directors, 10%+ owners). Buy/sell read from the filing's structured data — blank where a field isn't cleanly tagged.
Short interest
FINRA · bi-monthly| Settlement | Shares short | Days to cover | Δ vs prior |
|---|---|---|---|
| May 15, 2026 | 1.5M | 1.7 | +100.0% |
Shares sold short as reported to FINRA. Days-to-cover = short shares ÷ average daily volume — higher means more potential squeeze pressure.
Material events
SEC Form 8-K · most recentEvents the company reported on Form 8-K, labelled by the SEC item code it filed under — its own classification, not our interpretation.
Recent SEC filings
All filings ↗- SCHEDULE 13DMay 11, 2026
- SCHEDULE 13GMay 11, 2026
- 3OWNERSHIP DOCUMENTMay 6, 2026
- 3OWNERSHIP DOCUMENTMay 6, 2026
- 4May 6, 2026
- SCHEDULE 13DMay 6, 2026
- 4May 4, 2026
- 4May 4, 2026
- 4May 4, 2026
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